Are there adverse effects of diet, vitamin D3, and other factors on the recurrence of genital prolapse? To answer this question, Laktionova et al. (2024) examined the effect of diet and vitamin D3 on genital prolapse. The following are some of the key findings from the study:
- Lifestyle factors: the study found that weight lifting, heavy physical labor, constipation, insufficient protein intake, illnesses associated with prolonged coughing, and high body mass index (BMI) were associated with an increased likelihood of genital prolapse.
- Nutritional factors: insufficient protein intake was identified as one of the factors contributing to recurrence. In contrast, according to the study, weight loss of at least 5 kilograms showed a protective effect against recurrence.
- Vitamin D3: although specific effects directly related to vitamin D3 were not highlighted in the study, it is known that overall nutritional guidance can play an important role in reducing the risk of genital prolapse recurrence through immune support and general health maintenance.
- Postoperative monitoring: the importance of postoperative lifestyle monitoring and nutritional guidance cannot be overstated. Regular check-ups every six months for five years followed by annual visits help identify these factors and adjust for them among case groups.
In summary, although there is no direct evidence linking vitamin D3 specifically to reduced recurrence rates of genital prolapse, maintaining a healthy diet rich in protein along with other lifestyle adjustments such as regular exercise and avoiding heavy physical work can significantly reduce the risk of genital prolapse recurrence. Post-operative monitoring is also very important to effectively manage these factors.
How can BMI affect the likelihood of genital prolapse recurrence? BMI significantly affects the likelihood of recurrence of genital prolapse through several mechanisms, including:
- Increased abdominal pressure: A higher BMI is associated with increased abdominal pressure, which can exacerbate pressure on the pelvic support structures. This pressure may lead to a greater risk of prolapse or recurrence after surgical intervention.
- Pelvic floor support: obesity can impair the function of the pelvic floor muscles and connective tissues, thus weakening the support of the pelvic organs. This weakened support may contribute to a higher recurrence rate of genital prolapse.
- Inflammation and hormonal factors: increased body fat can lead to systemic inflammation and hormonal changes that can negatively impact tissue integrity and the post-operative healing process, potentially increasing the risk of recurrence.
- Surgical outcomes: studies have shown that patients with higher BMI may experience poorer surgical outcomes, including higher complication rates and recurrence after procedures aimed at correcting genital prolapse.
- Weight management: weight loss has been associated with improved pelvic floor health. Even modest weight loss (e.g., 5% of body weight) can reduce the risk of prolapse recurrence by relieving some of the pressure on the pelvic structures.
In summary, a higher BMI correlates with an increased likelihood of recurrence of genital prolapse due to factors such as increased abdominal pressure, impaired pelvic support, inflammatory response, and negative impact on surgical outcomes. Therefore, managing BMI through lifestyle interventions may be beneficial in reducing the recurrence rate of genital prolapse.
Effect of diet, vitamin D3 and other factors on genital prolapse recurrensce
Mariya Laktionova, Maksut Kulzhanov, Bayan Imasheva, Laura Serikkyzy, Zauresh Barmanasheva
This study addresses the pressing need for further investigation into risk factors contributing to genital prolapse recurrence, with a focus on factors like younger age and body mass index (BMI) that have been confirmed in the literature. Conducted as a cross-sectional study involving 300 post-operative cases of genital prolapse patients, the case groups comprising 210 individuals received regular gynecological check-ups every six months during the initial five years post-surgery, followed by annual visits, wherein lifestyle, diet, and laboratory values were monitored and adjusted. In contrast, the control group (90 patients) did not undergo post-operative gynecological follow-up. The results indicate that weight lifting, heavy physical work, menopause, constipation, insufficient protein intake, diseases associated with prolonged cough, and BMI are strongly associated with the likelihood of recurrent genital prolapse, while a weight reduction of 5 kg or more exhibits a protective effect (p<0.001). The established regression model proves statistically significant, explaining 84.1% of genital prolapse recurrence factors, with a sensitivity of 84.8% and specificity of 98.8%. These findings emphasize the importance of postoperative lifestyle monitoring, nutritional guidance, and immune support to reduce the risk of genital prolapse recurrence.
By: I. Busthomi
